Infographs - PROPOFOLOGY.COM

MIDAZOLAM - USES, ACTION & CAUTIONS

4/12/2016

J Rodriguez

11/10/2016 02:56:18 pm

The note about tautoterism and change in structure depending on its pH.
Its water soluble at a pH less than 4 and its imidazole ring is open. at body pH the rig closes, making it highly lipid soluble resulting in a rapid onset of action via IV adminstration.

Ref Anaesthesia and Intensivr care A-Z, Yentis, Hirsh and Ip. 5th edition

MIDAZOLAM - USES, ACTION & CAUTIONS

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MIDAZOLAM - USES, ACTION & CAUTIONS

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