PROPOFOLOGY.COM
  • Home
  • About
    • Donate
    • About >
      • Contributors
      • Why #FOAMed?
    • DISCLAIMER
  • FRCA COURSE
    • Buy FRCA Course
    • Tutorial List
    • International Course
  • BASICS OF CRITICAL CARE
  • Resources
    • Infographs >
      • Full List Index
      • Infograph Blog
      • Contribute
      • PDFs
    • Conferences >
      • ESICM Physiology 2020
      • ICSSOA 2019
      • ESICM LIVES 2019
      • ESICM LIVES 2018 >
        • LIVES 2018 CONTENT
      • IAEM 2018 >
        • Top 5 Studies IAEM
      • IFAD >
        • Case Report
        • The Hub
      • RAUK 2019
      • IFAD2018
      • IFAD2017 Blog
    • Trial Summaries
    • Index
    • Students
    • Absolute Beginner's Guide to Anaesthetics
    • Articles >
      • Articles
      • Tutorials
    • YouTube Channel
    • Anaesthetic Equipment
    • Contributions
    • Espanol
  • Podcasts
  • COVID19
    • Webinars COVID19
  • Anniversary Showcase

Vasopressors for Hypotensive Shock - Cochrane Review

3/18/2016

0 Comments

 
Cochrane Review
In summary, researchers reported no differences in total mortality in any comparisons of different vasopressors or combinations in any of the pre-defined analyses. More arrhythmias were found with dopamine.

"We found no evidence of substantial differences in total mortality between several vasopressors. Dopamine increases the risk of arrhythmia compared with norepinephrine and might increase mortality. Otherwise, evidence of any other differences between any of the six vasopressors examined is insufficient. We identified low risk of bias and high-quality evidence for the comparison of norepinephrine versus dopamine and moderate to very low-quality evidence for all other comparisons, mainly because single comparisons occasionally were based on only a few participants. Increasing evidence indicates that the treatment goals most often employed are of limited clinical value. Our findings suggest that major changes in clinical practice are not needed, but that selection of vasopressors could be better individualised and could be based on clinical variables reflecting hypo perfusion."
​
In summary, researchers reported no differences in total mortality in any comparisons of different vasopressors or combinations in any of the pre-defined analyses (evidence quality ranging from high to very low). More arrhythmias were observed in participants treated with dopamine than in those treated with norepinephrine (high-quality evidence). These findings were consistent among the few large studies and among studies with different levels of within-study bias risk.


0 Comments



Leave a Reply.

    USE OF THIS WEBSITE IS SUBJECT TO AGREEING TO THIS DISCLAIMER
    ​
    ​
    THIS WEBSITE IS FOR HEALTHCARE PROFESSIONALS & STUDENTS ONLY

    Categories

    All
    Airway
    Anaesthetic Technique
    Analgesia
    Anticoagulation
    Emergency
    Haematology
    ICU
    Metanalysis
    Nerve Blocks
    Pain Medicine
    Pharmacology
    Prehospital Medicine
    Resuscitation
    Sepsis
    Ultrasound

    Author

    Multiple authors from journals around the world that are free to read and disseminate. 
    ​
    There is no advice or recommendation  given about their content - only commentary.

    If you don't use 'Critical Care Reviews' by Rob MacSweeney - you need to start. The best website for free, open and online journal articles.
    Picture


    Archives

    May 2018
    April 2018
    December 2017
    January 2017
    June 2016
    April 2016
    March 2016

    RSS Feed

Creative Commons License
Free to access Propofology Infograms, eBooks and selected YouTube videos by Dr. David Lyness are licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Please attribute all works: 'Based on a work by Dr. David Lyness' at www.propofology.com/resources.
Home
About
Contact
ALL SITE USERS SHOULD READ AND AGREE TO THE DISCLAIMER HERE.
Contact via Twitter
  • Home
  • About
    • Donate
    • About >
      • Contributors
      • Why #FOAMed?
    • DISCLAIMER
  • FRCA COURSE
    • Buy FRCA Course
    • Tutorial List
    • International Course
  • BASICS OF CRITICAL CARE
  • Resources
    • Infographs >
      • Full List Index
      • Infograph Blog
      • Contribute
      • PDFs
    • Conferences >
      • ESICM Physiology 2020
      • ICSSOA 2019
      • ESICM LIVES 2019
      • ESICM LIVES 2018 >
        • LIVES 2018 CONTENT
      • IAEM 2018 >
        • Top 5 Studies IAEM
      • IFAD >
        • Case Report
        • The Hub
      • RAUK 2019
      • IFAD2018
      • IFAD2017 Blog
    • Trial Summaries
    • Index
    • Students
    • Absolute Beginner's Guide to Anaesthetics
    • Articles >
      • Articles
      • Tutorials
    • YouTube Channel
    • Anaesthetic Equipment
    • Contributions
    • Espanol
  • Podcasts
  • COVID19
    • Webinars COVID19
  • Anniversary Showcase